dog · investigational drug

Rapamycin for dog longevity

TRIAD is testing whether rapamycin affects lifespan and health measures in companion dogs; the trial is not proof that it works.

active controlled clinical research; efficacy not established
Short answer

Research to watch, not an owner-directed longevity treatment.

The atlas separates a biological hypothesis, a canine or feline measurement, a controlled clinical result and a commercial longevity claim. They are not interchangeable.

Evidence records

What was actually measured?

Lifespan Primary Purpose; Health Measures Secondary Purpose

multicentre randomised controlled clinical trial

TRIAD is a double-blind, placebo-controlled trial of rapamycin in companion dogs.

Population and result

generally healthy, older companion dogs meeting trial criteria · efficacy result not yet established in the cited official material

Limitation

Trial participation criteria do not define routine clinical use.

Safety And Use Boundary

official trial guidance

The official participant guidance says the effect on canine health and ageing is currently unknown and does not recommend owner-directed use.

Population and result

companion dogs outside the trial · use outside monitored research is not recommended by the study team

Limitation

Guidance is not a completed efficacy analysis.

Dose and safety boundary

No human-to-pet conversion.

Policy

No dose is provided. The Dog Aging Project states that it cannot ethically recommend use for age-related decline outside the monitored trial.

US regulatory context

“Pet supplement” is not a universal legal category.

FDA does not recognise a separate dietary-supplement category for animal products; depending on intended use, products are regulated as animal food or animal drugs. Disease-treatment or prevention claims can indicate new-animal-drug intent.

Open FDA source →
Sources and conflicts

Trace every material statement.

Dog Aging Project — Test of Rapamycin in Aging Dogsofficial study programme · 2026Open source →
Can I give my dog rapamycin on my own?official participant guidance · 2021Open source →

Page data version: 2026-08-18. Medical review is not claimed without a named sign-off.